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KMID : 1035420190070020141
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Journal of The Korean Society of Integrative Medicine
2019 Volume.7 No. 2 p.141 ~ p.151
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Antimicrobial and Cell Viability Measurement of Hypochlorous Acid against Streptococcus. mutans and Aggregatibacter. actinomycetemcomitans
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Song Ji-Yeon
Kim Ji-Young
Lee Kyung-Hee
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Abstract
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Purpose : The purpose of this study was to investigate the antimicrobial effect of hypochlorous acid (HOCL) in dental caries and periodontal disease. Experiments were conducted to observe wether alternative uses of HOCL for disinfectant.
Methods : The experimental solutions used in this study were divided into condition of HOCL and the comparative solutions. The stagnant HOCL solution was called pre-condition solution, and the HOCL solution prepared immediately after the treatment was called as post-condition solution. A commercially available disinfectant MAXCLEAN was used as positive control. In the comparative test solutions, S. mutans and A. actinomycetemcomitans were treated with gagrin and tap water filtered as a control. Number of viable cells were measured to confirm the antimicrobial effect and the degree of oral microorganism death following HOCL solution.
Results : The effect of HOCL in disk diffusion test showed no effect in the inhibition of oral bacteria growth. However, the antibacterial effect of gagrin was significantly high. In the measurement of viable cell counts in S. mutans, the HOCL showed more reduced the oral microorganisms after the treatment with the post-condition of HOCL solution than pre-condition of HOCL solution, but there was no significantly difference. In A. actinomycetemcomitans, HOCL solution showed no effect for disinfectant as compared with gagrin.
Conclusion : The antimicrobial effect of HOCL was shown to be low but it showed a slight disinfecting effect. In addition, as compared with the pre-condition solution of HOCL, the post-condition solution after oral treatment showed tend to reduce oral bacteria. Therefore, it is necessary to sufficiently control and remove the clinical using HOCL solution. Thus, the effect of HOCL on oral bacteria seems to have a similar effect to disinfection rather than sterilization.
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KEYWORD
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dental clinic, hypochlorous acid, HOCL, oral bacteria, oral gargling
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